Mathematical modeling And Fuzzy logic control of Inspired Isoflurane to obtain minimal flow of Anesthesia

In this paper, a fuzzy logic controller is designed and developed for control of Mean Arterial Pressure (MAP) of a patient during anesthesia using the anesthetic drug Isoflurane. Isoflurane is an anesthetic drug administered through a vaporizer based system. The main purpose of this paper is to provide a base for further real application .Here the patient is represented with a linear mathematical model that includes time delay elements. The parameters of the fuzzy controller are tuned in order to obtain a robust control performance .The simulation result showing the robust control performance of the proposed fuzzy controller under the parameter variations is given. Mean Arterial Pressure (MAP) is used as an inferential variable to indicate level of unconsciousness. Simulation experiments showed that excellent regulation of blood pressure around set point target. KeywordsMean Arterial pressure (MAP), anaesthesia,Isoflurane, fuzzy controller, robust control performance .